Karli Edholm, MD
News
Thrombectomy within Eight Hours of Stroke Onset Reduces Poststroke Disability
October 20, 2015
Clinical question: Does thrombectomy, in conjunction with medical therapy, improve functional independence in patients with an acute proximal anterior stroke? Background: Revascularization of proximal anterior strokes with alteplase alone occurs less than 50% of the time.
News
High-Flow Nasal Oxygen Therapy Noninferior to BiPAP in Post-Operative Respiratory Failure
October 6, 2015
Clinical question: In post-operative cardiothoracic surgery patients, is high-flow nasal oxygen therapy inferior to BiPAP for resolution of acute respiratory failure? Background: Acute respiratory failure is common following cardiothoracic surgery, and noninvasive ventilation often is used to avo
News
Supplemental Oxygen During STEMI Might Increase Myocardial Injury
October 6, 2015
Clinical question: Does routine oxygen supplementation in patients with STEMI increase myocardial injury? Background: Because of physiologic and clinical studies conducted before the era of acute coronary intervention, supplemental oxygen routinely is administered to patients with STEMI, regardle
News
Thrombectomy Within Eight Hours of Stroke Onset Reduces Post-Stroke Disability
October 6, 2015
Clinical question: Does thrombectomy, in conjunction with medical therapy, improve functional independence in patients with an acute proximal anterior stroke? Background: Revascularization of proximal anterior strokes with alteplase alone occurs less than 50% of the time.
News
Interdisciplinary Team Care on General Medical Units Does Not Improve Patient Outcomes
October 6, 2015
Clinical question: Does interdisciplinary care on general medical wards improve patient outcomes? Background: Patients on general medical wards might experience errors and/or preventable deaths.
News
Patient Satisfaction Scores, Objective Measures of Surgical Quality Have Positive Association
October 6, 2015
Clinical question: Is there an association between objective measures of surgical quality and patient satisfaction as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey? Background: The Centers for Medicare and Medicaid Services (CMS) has tied financi
News
Extended Anticoagulation Therapy and Recurrent Rates of Venous Thromboembolism
October 6, 2015
Clinical question: Among patients with a first episode of unprovoked pulmonary embolism (PE), what are the benefits and harms of extending the duration of anticoagulation for secondary prophylaxis against recurrent VTE? Background: Optimal duration of anticoagulation after initial unprovoked PE i
News
Wells Score Can’t Rule Out Deep Vein Thrombosis in Inpatient Setting
October 6, 2015
Clinical question: Should the Wells score be used for DVT risk stratification in the hospital? Background: The Wells score was derived to reduce lower extremity ultrasounds (LEUS) in the outpatient evaluation of DVTs.
News
Antibiotic Therapy, Appendectomy for Uncomplicated Acute Appendicitis
October 6, 2015
Clinical question: Is antibiotic therapy noninferior to appendectomy for treatment of uncomplicated acute appendicitis? Background: Previous randomized clinical trials have compared antibiotic therapy versus appendectomy for the treatment of uncomplicated, acute appendicitis.
News
Social, System Factors Can Influence Decisions to Continue Patient Care
October 6, 2015
Clinical question: Why do healthcare providers work while sick? Background: Healthcare providers generally are aware of the risks of infection to hospitalized patients; however, despite this knowledge, several studies have revealed providers continue to work while ill. Study design: Mixed-meth