Erik Greb joined the staff of Neurology Reviews in January 2012. Since then, he has attended scientific conferences, conducted video interviews, and written about clinical research in multiple sclerosis, epilepsy, Parkinson's disease, Alzheimer's disease, stroke, and other neurologic disorders. In addition to news articles, Erik has written investigative stories about multiple sclerosis, headache, and epilepsy. He previously wrote about pharmaceutical manufacturing, drug formulation and delivery, quality assurance, and regulation for Pharmaceutical Technology.
News
A large proportion of migraine patients are not offered preventive treatment
Among patients eligible for preventive therapy, more than a third were not offered this option, fewer than 10% were currently taking preventive...
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Almost half of patients with migraine are reluctant to seek care
Common reasons for failure to seek treatment included believing that migraine was not severe enough to warrant a consultation, worries about cost...
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A new biomarker of traumatic brain injury?
“Von Willebrand factor may be more specific for acute injuries, given that it does not seem to stay chronically elevated.”
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NfL beats T-tau as a prognostic marker of cognitive decline
NfL was cross-sectionally associated with most cognitive outcomes; longitudinally, higher NfL at baseline was associated with cognitive decline in...
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Investigational drug reduces brain lesions in highly active MS
Tolebrutinib, a BTK inhibitor, reduced new gadolinium-enhancing lesions and new and enlarging T2 lesions.
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Long-term benefit for DBS in treating Parkinson’s disease motor symptoms
“Both STN and GPi DBS maintained motor benefit out to 10 years, with improvements seen in tremor and rigidity, greater than bradykinesia.”
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Intranasal third-generation CGRP effective for acute migraine
Among patients taking zavegepant, more than 20% achieved pain freedom and 40% were relieved of their most bothersome symptom.
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Radially adjustable ‘Tigertriever’ safe, effective in stroke
The novel device may increase the options for endovascular therapy.
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Neurologic drug prices jump 50% in five years
Most of the increased cost was due to rising costs for neuroimmunology drugs, mainly for those used to treat multiple sclerosis (MS).
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EEG data may help aid diagnosis, treatment of focal epilepsy
“A patient with epilepsy may have a unique combination of seizure rhythms that can inform the days and timing of his or her highest seizure risk...
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Prostate drugs tied to lower risk for Parkinson’s disease
If confirmed by additional trials, glycolysis-enhancing drugs could be a new option to slow progression of Parkinson’s disease,
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Researchers examine factors associated with opioid use among migraineurs
Despite ample evidence of opioids’ harmful effects when administered for migraine, about one-third of migraineurs report taking them.
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Blood biomarker may predict Alzheimer’s disease progression
P-tau181 and NfL in blood have individual and complementary potential roles in the diagnosis and the monitoring of neurodegenerative disease.