Erik Greb joined the staff of Neurology Reviews in January 2012. Since then, he has attended scientific conferences, conducted video interviews, and written about clinical research in multiple sclerosis, epilepsy, Parkinson's disease, Alzheimer's disease, stroke, and other neurologic disorders. In addition to news articles, Erik has written investigative stories about multiple sclerosis, headache, and epilepsy. He previously wrote about pharmaceutical manufacturing, drug formulation and delivery, quality assurance, and regulation for Pharmaceutical Technology.
News
Researchers identify five cognitive phenotypes in MS
Clinical and imaging examinations suggest discrete profiles of cognitive dysfunction with distinct neuroanatomical foundations.
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High plasma GFAP level predicts disability accumulation in secondary progressive MS
The GFAP level may be a stronger predictor in women and in patients with nonactive disease, compared with active disease.
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Satralizumab reduces risk of severe NMOSD relapse
The treatment also was linked to a lower likelihood of receiving acute relapse therapy, but the study’s sample size was low.
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Exposure to DMT may delay disability accumulation in primary progressive MS
Longer exposure to treatment is associated with a reduced risk of being restricted to a wheelchair in this patient population.
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Mortality burden of dementia may be greater than estimated
The mortality burden of dementia may be highest among non-Hispanic black people, compared with people of other races.
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Alzheimer’s disease may affect sleep patterns
Disturbed sleep does not appear to cause Alzheimer’s disease and Alzheimer’s disease does not appear to cause major depressive disorder.
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Concussion linked to risk for dementia, Parkinson’s disease, and ADHD
A history of multiple concussions strengthened the association between concussion and subsequent mood and anxiety disorder, dementia, and...
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Consensus document reviews determination of brain death
The recommendations are the minimum criteria for the determination of brain death or death by neurologic criteria.
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Cardiovascular risk factors tied to midlife cognitive decline
Hypertension, diabetes, and smoking can affect cognition at an age much younger than previously believed.
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Less REM sleep tied to higher mortality
Less REM sleep is associated with an increased risk for death in middle-aged and older adults.
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Can DBS in early Parkinson’s disease reduce disease progression?
Compared with standard treatment, DBS plus drug therapy appears to reduce the need for polypharmacy.
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Migraine is often a deciding factor in pregnancy planning
Among women with migraine, those who were younger, had menstrual migraine, or had chronic migraine were more likely to decide to not become...
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Consistent effects for galcanezumab in cluster headache
Most patients whose PGI-I score improved in one cluster bout also improved in a subsequent bout.
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Headache may predict clinical evolution of COVID-19
Headache onset could occur during the presymptomatic or symptomatic phase of COVID-19 and could resemble tension-type or migraine headache.