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An Official Publication of
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Brian Markoff, MD, FHM

  • News

    Cardiovascular Disease and Risk of Hip Fracture

    October 27, 2014

    Clinical question: Is the diagnosis of cardiovascular disease (CVD) associated with the risk of subsequent hip fracture? Background: Osteoporosis and CVD are regarded as independent, age-related conditions.

  • News

    OTC Analgesics Not Associated with Acute Decompensation in Cirrhotic Patients

    October 27, 2014

    Clinical question: Do over-the-counter (OTC) analgesics lead to acute hepatic decompensation among patients with cirrhosis? Background: In theory, intake of acetaminophen and/or nonsteroidal anti-inflammatory drugs (NSAIDs) can worsen hepatic function and lead to complications among cirrhotic pat

  • News

    Lower Perioperative Mortality with Endovascular Vs. Open Abdominal Aortic Aneurysm Repair

    October 27, 2014

    Clinical question: How do perioperative and long-term morbidity and mortality compare in endovascular and open repair of abdominal aortic aneurysm (AAA)? Background: Open AAA repair has relatively high perioperative mortality.

  • News

    Discontinuation of Beta Blockers Increases Risk of Postoperative Myocardial Infarction and Death

    October 27, 2014

    Clinical question: Does perioperative beta-blocker discontinuation affect postoperative myocardial infarction (MI) in low-risk patients undergoing joint arthroplasty? Background: Recent trials show no benefit of perioperative beta blockers in reducing the incidence of perioperative myocardial inf

  • News

    Cancer Guideline for VTE Prophylaxis for Inpatients and Long-Term Treatment With Low-Molecular-Weight Heparin for Acute VTE

    October 27, 2014

    Clinical question: On what aspects of VTE management in cancer patients are there consensus among the major guideline panels? Background: VTE is a common and serious complication of cancer.

  • News

    Trauma Patients with Pulmonary Embolism Might Not Have DVT on Imaging of Lower Extremities

    October 27, 2014

    Clinical question: What is the relationship between acute DVT and pulmonary embolism (PE) in trauma patients? Background: Major trauma is associated with an increased risk of acute DVT and PE. It is assumed that the majority of PEs arise from DVTs in the lower extremities.

  • News

    Eliminating Adverse Events and Redundant Tests Could Generate U.S. Healthcare Savings

    October 27, 2014

    Clinical question: Using available data, what is the estimated cost savings of eliminating adverse events and avoiding redundant tests? Background: Reimbursement schemes are changing such that hospitals are reimbursed less for some adverse events.

  • News

    High Perioperative Oxygen Fraction Does Not Improve Surgical-Site Infection Frequency after Abdominal Surgery

    October 27, 2014

    Clinical question: Does the use of 80% oxygen perioperatively in abdominal surgery decrease the frequency of surgical-site infection within 14 days without increasing the rate of pulmonary complications? Background: Low oxygen tension in wounds can negatively impact immune response and healing.

  • News

    In the Literature: HM-Related Research You Need to Know

    February 2, 2011

    Physician reviews of effects of extended VTE prophylaxis in medical patients, outcomes with and without preprocedural statins, association of subclinical hypothyroidism and CHD, and more

  • News

    In the Literature: February 2010

    February 2, 2010

    The latest HM-related research you need to know

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