Brian Markoff, MD, FHM
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Cardiovascular Disease and Risk of Hip Fracture
October 27, 2014
Clinical question: Is the diagnosis of cardiovascular disease (CVD) associated with the risk of subsequent hip fracture? Background: Osteoporosis and CVD are regarded as independent, age-related conditions.
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OTC Analgesics Not Associated with Acute Decompensation in Cirrhotic Patients
October 27, 2014
Clinical question: Do over-the-counter (OTC) analgesics lead to acute hepatic decompensation among patients with cirrhosis? Background: In theory, intake of acetaminophen and/or nonsteroidal anti-inflammatory drugs (NSAIDs) can worsen hepatic function and lead to complications among cirrhotic pat
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Lower Perioperative Mortality with Endovascular Vs. Open Abdominal Aortic Aneurysm Repair
October 27, 2014
Clinical question: How do perioperative and long-term morbidity and mortality compare in endovascular and open repair of abdominal aortic aneurysm (AAA)? Background: Open AAA repair has relatively high perioperative mortality.
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Discontinuation of Beta Blockers Increases Risk of Postoperative Myocardial Infarction and Death
October 27, 2014
Clinical question: Does perioperative beta-blocker discontinuation affect postoperative myocardial infarction (MI) in low-risk patients undergoing joint arthroplasty? Background: Recent trials show no benefit of perioperative beta blockers in reducing the incidence of perioperative myocardial inf
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Cancer Guideline for VTE Prophylaxis for Inpatients and Long-Term Treatment With Low-Molecular-Weight Heparin for Acute VTE
October 27, 2014
Clinical question: On what aspects of VTE management in cancer patients are there consensus among the major guideline panels? Background: VTE is a common and serious complication of cancer.
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Trauma Patients with Pulmonary Embolism Might Not Have DVT on Imaging of Lower Extremities
October 27, 2014
Clinical question: What is the relationship between acute DVT and pulmonary embolism (PE) in trauma patients? Background: Major trauma is associated with an increased risk of acute DVT and PE. It is assumed that the majority of PEs arise from DVTs in the lower extremities.
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Eliminating Adverse Events and Redundant Tests Could Generate U.S. Healthcare Savings
October 27, 2014
Clinical question: Using available data, what is the estimated cost savings of eliminating adverse events and avoiding redundant tests? Background: Reimbursement schemes are changing such that hospitals are reimbursed less for some adverse events.
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High Perioperative Oxygen Fraction Does Not Improve Surgical-Site Infection Frequency after Abdominal Surgery
October 27, 2014
Clinical question: Does the use of 80% oxygen perioperatively in abdominal surgery decrease the frequency of surgical-site infection within 14 days without increasing the rate of pulmonary complications? Background: Low oxygen tension in wounds can negatively impact immune response and healing.
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In the Literature: HM-Related Research You Need to Know
February 2, 2011
Physician reviews of effects of extended VTE prophylaxis in medical patients, outcomes with and without preprocedural statins, association of subclinical hypothyroidism and CHD, and more
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In the Literature: February 2010
February 2, 2010
The latest HM-related research you need to know
