Article
Comparative Efficacy and Safety of Clopidogrel Versus Aspirin Monotherapy in Patients with Established CAD
- Micaela Danila Monteagudo, MD
April 6, 2026
CLINICAL QUESTION: Does monotherapy with clopidogrel reduce the risk of major adverse cardiovascular or cerebrovascular events (MACCE) compared to monotherapy with aspirin in patients with...
Article
Optimal Timing of Anticoagulation Initiation After Ischemic Stroke in Patients with AF
- Gonzalo Grondona Fernández, MD
April 6, 2026
CLINICAL QUESTION: In patients with atrial fibrillation (AF) and acute ischemic stroke, does early anticoagulation initiation (within four days) improve outcomes compared to delayed...
Article
Optimal Management of Febrile Neutropenia in Oncologic and Oncohematologic Patients
- Patricio Agustín Vernengo, MD
April 6, 2026
CLINICAL QUESTION: Is initial empiric antibiotic coverage important in patients with febrile neutropenia? How should the therapeutic strategy be defined? BACKGROUND: Febrile neutropenia is defined...
Article
Low-Dose Glucocorticoids Reduce Mortality in CAP
April 6, 2026
CLINICAL QUESTION: Do glucocorticoids reduce mortality in hospitalized adults with community-acquired pneumonia in a resource-limited setting? BACKGROUND: The use of glucocorticoids as adjunctive...
Article
Invasive Versus Conservative Strategy in Older Adults with NSTE-ACS: Fewer Infarctions Without a Mortality Benefit
- Juan Patricio Furlong, MD
April 6, 2026
CLINICAL QUESTION: In patients aged 70 years or older with non–ST-segment elevation acute coronary syndrome (NSTEACS), does an invasive strategy reduce mortality and cardiovascular events compared...
Article
The Apparent Increase in the Incidence of Early-Onset Cancer in the U.S. Population
April 6, 2026
CLINICAL QUESTION: Does the observed rise in cancer rates reflect a true increase in incidence, or is it primarily attributable to heightened diagnostic scrutiny? BACKGROUND: In recent years, the...
Article
What’s New in the 2025 IDSA Updates for Complicated UTIs?
- Ali Farkhondehpour, MD, FACP, SFHM;
- Annie Cowell, MD, MPH, FIDSA
April 6, 2026
Case: An 80-year-old man with Alzheimer’s dementia presents with fever, worsening suprapubic discomfort, and new right flank pain. He began ciprofloxacin the day before for a presumed urinary tract...
Article
The Wellness Paradox: Reconciling Care and Cost in Hospital Medicine
April 6, 2026
The hospital’s hum never really stops, regardless of the hour. Whether you’re rounding on days or doing admissions on nights, the demands are constant, and the line between doing good work and...
Article
Laying the Groundwork for Sustainable Overnight Care
- Alexandra Kilinsky, DO, MS;
- Jennifer Reese, MD;
- Jennifer Sedler, MD;
- Justin Lockwood, MD, MSCS;
- Kyle Pronko, MD;
- Lauren Anderson, MD;
- Sonja I. Ziniel, PhD, MA
April 6, 2026
Pediatric hospital medicine (PHM) programs with nocturnists have more than doubled in recent years.¹ Consequently, more hospitalists face the hazards of overnight work, including sleep-related...
Article
Getting an Advanced Degree—Why Bother?
April 6, 2026
An increasing number of doctors, including hospitalists, are pursuing advanced degrees beyond their medical degrees, driven by intellectual curiosity, the belief that such a degree is necessary for...