News
D-dimer thresholds rule out PE in meta-analysis
Publish date: December 14, 2021
Data from a large review support use of D-dimer levels to diagnose PE without imaging.
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Apixaban outmatches rivaroxaban for VTE in study
Publish date: December 6, 2021
These real-world findings may guide selection of initial anticoagulant therapy, according to authors of the paper.
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D-dimer unreliable for ruling out pulmonary embolism in COVID-19
Publish date: October 14, 2021
“These results suggest that use of D-dimer levels to exclude PE among patients hospitalized with COVID-19 may be inappropriate and have limited clinical utility.”
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Rivaroxaban’s single daily dose may lead to higher bleeding risk than other DOACs
Publish date: October 11, 2021
Corroborating previous studies, Iceland researchers report that rivaroxaban poses the highest risk of GI bleeding, compared with other DOACs.
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Refined heart rate cutoffs may improve prognostic value of acute PE scoring systems
Publish date: September 21, 2021
In an observational registry-based study, dropping the 110-bpm heart rate threshold improved sensitivity for low-risk PE, while increasing it improved specificity for intermediate-high–risk PE.
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Study gives bleeding risk estimates for VTE patients on anticoagulants
Publish date: September 13, 2021
New research provides best available estimates of long-term bleeding risk with different anticoagulants, authors say.
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Prophylactic anticoagulation tied to lower death rate in COVID
Publish date: June 18, 2021
Prophylactic use of low-dose anticoagulation to prevent venous thromboembolism was associated with reduced 60-day mortality in patients hospitalized with COVID-19 in Michigan.
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Factor XI inhibitor–based anticoagulation strategies gain ground
Publish date: November 18, 2020
“When we compare the FXI inhibitors with existing anticoagulants, we don’t necessarily want to go up against the DOACs.”
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HOME-PE trial clarifies which pulmonary embolism patients to treat at home
Publish date: September 1, 2020
“Who’s happy with the HOME-PE trial? I think everybody.” – Dr. Stavros V. Konstantinides
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PCSK9 inhibitors unexpectedly link with lower VTE, aortic stenosis
Publish date: April 21, 2020
Post hoc analyses of data from as many as 46,000 patients showed surprising links between PCSK9 inhibition and reduced rates of VTE and aortic stenosis.
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