Neurology
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FDA approves generic naloxone spray for opioid overdose treatment
The agency said the naloxone nasal spray does not need assembly and can be used by anyone, regardless of medical training.
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FDA to expand opioid labeling with instructions on proper tapering
The label changes are intended to be used when both the clinician and patient have agreed to reduce the opioid dosage.
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Report calls for focus on ‘subpopulations’ to fight opioid epidemic
“Methadone, buprenorphine, and extended-release naltrexone ... save lives” but most people with OUD get no treatment, new report says.
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Better communication with pharmacists can improve postop pain control
A pharmacist advises surgeons to make sure to adjust medications based on preoperative or intraoperative doses to avoid endangering patients by...
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Surge of gabapentinoids for pain lacks supporting evidence
Review of 54 papers for gabapentin and 30 for pregabalin finds little evidence for effective pain control in off-label uses.
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Intensive blood pressure lowering may not reduce risk of recurrent stroke
HONOLULU – Intensive treatment significantly reduces blood pressure, compared with standard treatment, and is...
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Andexanet alfa effectively reverses factor Xa inhibition
HONOLULU – The drug establishes good or excellent hemostasis in 82% of patients with acute major bleeding associated...
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Higher blood pressure after thrombectomy links with bad stroke outcomes
HONOLULU – Observational data showed that ischemic stroke patients with systolic blood pressure above 158 mm Hg after thrombectomy had worse...
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Glyceryl trinitrate does not improve outcomes of ischemic stroke
HONOLULU – Although treatment reduced blood pressure, it did not reduce disability at 90 days, compared with sham....
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Noncardiac surgery has 7% covert stroke rate in elderly
HONOLULU – Covert strokes were linked with a doubled rate of cognitive decline in older patients after noncardiac surgery.