Article
When Less Is More: Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation
June 18, 2026
Mount Sinai Med-Lit Review Clinical Question: In patients with chronic coronary syndrome and high atherothrombotic risk on long-term oral anticoagulation, does the addition of aspirin improve...
Article
Evaluation of Optimal Duration of DAPT After PCI When Stratified by Bleeding Risk
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: What is the optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) with drug-eluting stent (DES) placement...
Article
High-Normal Potassium Levels Reduce Ventricular Arrhythmias and Related Adverse Outcomes in High-Risk Patients with ICDs
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Does actively increasing serum potassium to the high-normal range (4.5 to 5.0 mmol/L) reduce malignant ventricular arrhythmias, arrhythmia-related...
Article
Acetylcholinesterase Inhibitors for Delirium Prevention: A Systematic Review and Meta-Analysis
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Do acetylcholinesterase inhibitors help reduce the occurrence and severity of delirium in hospitalized patients? Background: Delirium is a frequent...
Article
Beta-Blockers after Myocardial Infarction without Reduced Ejection Fraction
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Are beta-blockers beneficial in patients discharged after receiving invasive care for a myocardial infarction (MI) and with preserved left ventricular...
Article
Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury: BICARICU-2
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Does sodium bicarbonate infusion in patients with moderate to severe acute kidney injury and severe metabolic acidosis reduce 90-day all-cause...
Article
Peripheral Vasopressors Safe in Early Sepsis Resuscitation
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Can vasopressors be safely administered through a peripheral line? Background: Traditionally, clinicians have administered vasopressors through central...
Article
Extended Low-Dose Apixaban After Provoked VTE Reduces Recurrence in Selected Patients
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Among patients with provoked venous thromboembolism (VTE) and ongoing risk factors, does extending anticoagulation with low-dose apixaban reduce...
Article
Aficamten Monotherapy is Superior to Metoprolol Monotherapy for Patients with Symptomatic Obstructive Hypertrophic Cardiomyopathy
April 9, 2026
NYU Langone Health Med-Lit Review Clinical Question: Is aficamten monotherapy superior to metoprolol monotherapy for patients with symptomatic obstructive hypertrophic cardiomyopathy? Background:...
Article
Beta-Blockers After MI in Patients Without Heart Failure
April 9, 2026
NYU Langone Health Med-Lit Review Clinical Question: Does long-term beta-blocker therapy lower death or major adverse cardiovascular events in post-myocardial infarction (MI) patients with preserved...