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In some lymphomas, ibrutinib yields “almost unheard-of” survival rates
Adding ibrutinib to standard chemotherapy improves DLBCL survival in younger patients, especially among certain genetic subtypes.
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Cancer-related thyroidectomy linked to increased diabetes risk
Compared with nonthyroid cancer patients, those receiving thyroidectomy for thyroid cancer show up to a 40% greater risk for diabetes.
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Treating ALL: Asparaginase enzyme levels linked to toxicities
New data suggest benefits of drug monitoring to assess risks for pancreatitis and other toxicities.
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U.S. obesity rates soar in early adulthood
Interventions during ages 18-25 seen as key to shift unhealthy trajectory.
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ADVOCATE: Avacopan shows renal benefits in ANCA vasculitis
A subanalysis of renal effects in the phase 3 ADVOCATE trial found that avacopan improved estimated glomerular filtration rate best among patients...
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Specific blood pressure-lowering drugs prevent onset of new diabetes
Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers showed the strongest association with preventive effects.
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B-cell repletion is common with MS drug, but no symptom worsening
While “surprising,” these findings do not prove that B-cell repletion does not put someone at risk.
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Brief, automated cognitive test may offer key advantages in MS
The automated NIH Toolbox Cognition Battery may be used as an alternative to other gold-standard measures which may cover limited domains or...
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Specialty pharmacists may speed time to MS treatment
Because there currently is no established DMT selection algorithm, specialty pharmacists can assist in medication education and management.
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Cannabis use common for MS-related spasticity
The new data reflect the latest patterns of use amid sweeping changes in recreational and medical marijuana laws.
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New consensus guideline on clinical MRI use in MS
The updated protocol is beneficial in providing “simple, reasonable guidelines that can be easily acquired at almost any imaging location in the U...
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Two diets linked to improved cognition, fatigue in MS
These results are among the first to show diet-related favorable reductions in cognitive dysfunction.
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Vitamin D status may play a pivotal role in colon cancer prevention
Observational studies, plus laboratory and mouse model studies, point to a higher risk of colorectal cancer when vitamin D levels are low....