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Anecdotal Failures in the Diagnosis of Serotonin Syndrome

Clinical Question: What is the validity of commonly held beliefs regarding serotonin syndrome (SS)? Background: SS is a potentially life-threatening condition caused by serotonin excess in the central nervous system. The authors tested the validity of four widely accepted tenets about SS: that the Hunter criteria are superior, that the onset of SS is rapid… [Read More]

Restrictive Blood Transfusion Strategies May Increase the Risk of Mortality, Morbidity for Elderly Patients Undergoing Orthopedic Surgery

Are there particular groups of patients in which lower transfusion thresholds (transfusion only at lower hemoglobin levels) may be harmful?